Cure Alzheimer’s Fund Awards Grant to University of Colorado


Cure Alzheimer’s Fund Awards Grant to University of Colorado School of Medicine Researcher to Investigate Alzheimer’s Disease Treatments

Boston – Cure Alzheimer’s Fund recently awarded Dr. Nicholas Seeds, with the University of Colorado School of Medicine, a $100,000 grant for novel research on Alzheimer’s disease, which affects 5.2 million Americans and their families and is the most common cause of dementia in the elderly.

“This research has the potential to unlock a new understanding of the causes and risk factors for Alzheimer’s disease,” said Tim Armour, President and CEO of Cure Alzheimer’s Fund. “It could bring us a step closer to ultimately stopping or even reversing its effects.”

The grant will allow Seeds’ lab to continue research on neuroserpin, a protease inhibitor in the brain that is a possible contributor to the onset of Alzheimer’s. The lab’s research on mice shows that the deletion of the neuroserpin gene can lead to a reduction of Amyloid-Beta, a protein in the brain that is commonly linked to Alzheimer’s disease, and may result in restoration of normal cognitive behavior. Most importantly, Seeds aims to identify small molecules that block neuroserpin. The goal is to create Alzheimer’s therapeutics for future patient studies.

“With university budgets stretched thin, the Fund’s support is critical in helping further this important research on this devastating disease,” said Seeds, a Professor of Biochemistry and Molecular Genetics at the Colorado medical school.

Cure Alzheimer’s Fund has no endowment and passes funds raised directly to selected research. The Fund has no financial or intellectual property interest in the research funded, and will make known the results of all funded research as soon as possible. Over the past ten years the federal government’s investment in Alzheimer’s research and education has decreased. Since it’s inception in 2004, Cure Alzheimer’s Fund has raised more than $15 million, investing all of it directly into research.

“Research is key to finding a cure and better treatments for Alzheimer’s disease,” said Armour. “With the advances in technology over the past 10 years, great strides have been made in Alzheimer’s research and we are on the cusp of major breakthroughs. Cure Alzheimer’s Fund believes the pioneering work of the University of Colorado School of Medicine researchers and others could bring us one step closer to our goal of finding a cure.”